Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 13/20 | 0.45 |
| ▸ | CA2 | P00918 | 13/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557327 | 0.87 | MAPT (0.56) | MMP2MAPTPOLBBLMCA1 | |
| SCHEMBL11555762 | 0.87 | PTGS1 (0.50) | MMP2MAPTPOLBBLMCA1 | |
| SCHEMBL11552088 | 0.84 | CA12 (0.43) | MMP2MAPTPOLBBLMCA1 | |
| SCHEMBL942895 | 0.78 | MMP2 (0.64) | MMP2MAPTPOLBCA1CA2 | |
| SCHEMBL2981080 | 0.78 | ALDH1A1 (0.53) | MAPTKDM4ELMNAHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL11556095 | 0.75 | MAPT (0.51) | MMP2MAPTPOLBBLMCA1 | |
| SCHEMBL942007 | 0.75 | MMP2 (0.60) | MMP2POLBCA1CA2CA12 | |
| SCHEMBL938180 | 0.75 | MMP2 (0.60) | MMP2CA1CA2CA12CA9 | |
| SCHEMBL11554086 | 0.74 | MAPT (0.55) | MMP2MAPTPOLBBLMCA1 | |
| SCHEMBL939846 | 0.74 | MMP2 (0.50) | MMP2MAPTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |