Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL7519368 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668544 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21937 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668547 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL63463 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119280450-A | Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof | 孙国明 | 2025-01-10 | — | — | CN | claimed |
| CN-118844448-A | Preparation method of long-acting antibacterial liquid | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| CN-118844836-A | Long-acting disinfection and sterilization wet (towel) paper | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| US-11518868-B2 | Laser transmissive compositions and related methods | APTIV LIMITED TECHNOLOGIES | 2022-12-06 | — | — | US | claimed |
| US-20220135772-A1 | LASER TRANSMISSIVE COMPOSITIONS AND RELATED METHODS | APTIV TECHNOLOGIES LIMITED (BB) | 2022-05-05 | — | — | US | claimed |
| CN-114085616-A | Lithium tantalate material chemical mechanical polishing solution based on silicon dioxide nano abrasive and preparation method thereof | 河北工业大学 | 2022-02-25 | — | — | CN | claimed |
| US-10975256-B2 | Ink compositions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-04-13 | — | — | US | claimed |
| US-10920095-B2 | Ink compositions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-02-16 | — | — | US | claimed |
| US-7892351-B1 | Composition of materials and processes for making boroncitrates to create cements with field adjustable set times | W.D. KIRKPATRICK ENTERPRISES LLC | 2011-02-22 | — | — | US | claimed |
| US-7854803-B1 | Composition of materials and processes of making boroncitrates to establish set times for hydraulic cements | W.D. KIRKPATRICK ENTERPRISES LLC | 2010-12-21 | — | — | US | claimed |
| EP-1372631-A4 | METHOD AND FORMULA FOR ANTI-TUMOR AND ANTI-MATASTATIC EFFECT | GILES BRIAN C (US) | 2005-07-27 | — | — | EP | claimed |
| EP-1554229-A1 | FLAME RETARDANT AND MICROBE INHIBITING METHODS AND COMPOSITIONS | SMT, INC. (US) | 2005-07-20 | — | — | EP | claimed |
| US-20040253323-A1 | Ionic cancer therapy and methods for using same in the treatment of tumors and metastasis | GILES BRIAN C (US) | 2004-12-16 | — | — | US | claimed |
| EP-1372631-A1 | METHOD AND FORMULA FOR ANTI-TUMOR AND ANTI-MATASTATIC EFFECT | Giles, Brian C. (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2004000758-A1 | FLAME RETARDANT AND MICROBE INHIBITING METHODS AND COMPOSITIONS | SMT, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| US-20030170317-A1 | Flame retardant and microbe inhibiting methods and compositions | SMT, INC. | 2003-09-11 | — | — | US | claimed |
| WO-2001015745-A9 | METHOD AND FORMULA FOR TUMOR REMISSION AND SUPPRESSION OF CANCER | GILES BRIAN C (US) | 2002-11-07 | — | — | WO | claimed |
| WO-2002069955-A1 | METHOD AND FORMULA FOR ANTI-TUMOR AND ANTI-MATASTATIC EFFECT | GILES BRIAN C (US) | 2002-09-12 | — | — | WO | claimed |
| EP-1229942-A1 | METHOD AND FORMULA FOR TUMOR REMISSION AND SUPPRESSION OF CANCER | Giles, Brian C. (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001015745-A1 | METHOD AND FORMULA FOR TUMOR REMISSION AND SUPPRESSION OF CANCER | GILES BRIAN C (US) | 2001-03-08 | — | — | WO | claimed |