SCHEMBL2644008

SCHEMBL2644008

CC(O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
TYR P14679 1/20 0.50
PTPN5 P54829 1/20 0.47
TSHR P16473 3/20 0.46
NR1H4 Q96RI1 2/20 0.44
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 2/20 0.43
GRIA4 P48058 2/20 0.43
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
HDAC1 Q13547 1/20 0.40
UGT2B7 P16662 1/20 0.40
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18282984 1.00 LMNA (0.50) LMNATYRPTPN5TSHRNR1H4
SCHEMBL30010731 1.00 LMNA (0.50) LMNATYRPTPN5TSHRNR1H4
SCHEMBL14230569 0.88 CYP1A2 (0.52) LMNATYRPTPN5NR1H4ALDH1A1
SCHEMBL7948388 0.85 ESR1 (0.50) LMNATYRPTPN5TSHRNR1H4
SCHEMBL31201776 0.83 PTPN5 (0.46) LMNAPTPN5NR1H4ALDH1A1NOS3
SCHEMBL3586191 0.82 LMNA (0.52) LMNATYRTSHRNR1H4ALDH1A1
SCHEMBL3692155 0.82 LMNA (0.52) LMNATYRTSHRNR1H4ALDH1A1
SCHEMBL20752299 0.82 LMNA (0.52) LMNATYRTSHRNR1H4ALDH1A1
SCHEMBL10708786 0.82 LMNA (0.52) LMNATYRTSHRNR1H4ALDH1A1
SCHEMBL1332759 0.81 PTPN5 (0.44) LMNATYRPTPN5TSHRNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117982698-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2024-05-07 CN claimed
CN-111039750-B Method for preparing 4-tert-butyl phenethyl alcohol 盐城工学院 2020-12-22 CN claimed
CN-111039750-A Method for preparing 4-tert-butyl phenethyl alcohol 盐城工学院 2020-04-21 CN claimed
US-5446227-A Contacting alpha-methyl benzylic hydroperoxide with organic sulfide to produce corresponding hydroxide and oxygenated sulfur compound, treating hydroxide with base PHILLIPS PETROLEUM COMPANY (US) 1995-08-29 US claimed
EP-4709725-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Progentos Therapeutics, Inc. (US) 2026-03-18 EP disclosed
CN-119977739-A Method for preparing nitrile compound by oxidizing alcohol compound to break C-C bond 中国科学院大连化学物理研究所 2025-05-13 CN disclosed
CN-119798058-A Preparation method of alpha-alkyl ketone derivative 浙江工业大学 2025-04-11 CN disclosed
CN-116693467-B Thiazole amine MBL inhibitor and preparation method and application thereof 四川大学 2025-02-14 CN disclosed
CN-119243184-A Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent 国网安徽省电力有限公司电力科学研究院 2025-01-03 CN disclosed
CN-118993945-A Acetophenone hydrazone compound 上海泰初化工技术有限公司 2024-11-22 CN disclosed
WO-2024233642-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PROGENTOS THERAPEUTICS, INC. (US) 2024-11-14 WO disclosed
CN-117982698-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2024-05-07 CN disclosed
EP-0134439-B1 PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF AND INSECTICIDAL, ACARICIDAL, FUNGICIDAL COMPOSITIONS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-08-24 EP disclosed
EP-0134439-A1 Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-03-20 EP disclosed
US-4233467-A Dehydration of α-methylbenzyl alcohols to form monovinylidene aromatic monomers THE DOW CHEMICAL COMPANY (US) 1980-11-11 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4150059-A Dehydration of alpha-methylbenzyl alcohols over silica to form monovinylidene aromatic monomers THE DOW CHEMICAL COMPANY (US) 1979-04-17 US disclosed
US-4144272-A REACTING SECONDARY AMINE WITH CARBON DISULFIDE, OXIDATION OF DITHIOCARBAMATE INTERMEDIATE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-03-13 US disclosed
US-4143045-A METHOD OF PREPARING DIBENZOTHIAZOLYL DISULFIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-03-06 US disclosed
US-4049736-A SILICA GEL CATALYST THE DOW CHEMICAL COMPANY (US) 1977-09-20 US disclosed