Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026357 | 0.87 | POLB (0.65) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL7980944 | 0.87 | GSTO1 (0.58) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| Diapamide SCHEMBL119354 | 0.85 | GSTO1 (0.54) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| Diapamide SCHEMBL27555055 | 0.85 | GSTO1 (0.54) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL11595632 | 0.84 | POLB (0.54) | POLBHSD17B10KDM4EL3MBTL1MAPT | |
| SCHEMBL13543283 | 0.84 | GSTO1 (0.52) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL13545186 | 0.83 | GSTO1 (0.55) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL10962880 | 0.83 | GSTO1 (0.62) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL7967267 | 0.81 | GSTO1 (0.53) | GSTO1POLBHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL15959250 | 0.80 | GSTO1 (0.49) | GSTO1POLBHSD17B10KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |