Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560328 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDMAPTALDH1A1GAA | |
| SCHEMBL11558024 | 0.77 | KMT2A (0.45) | SMN1; SMN2LMNARAB9AKDM4EMAPT | |
| SCHEMBL2656435 | 0.76 | HTT (0.51) | SMN1; SMN2HTTP2RX7NPSR1HPGD | |
| SCHEMBL11563998 | 0.75 | TAAR1 (0.42) | HPGDKDM4EMAPTPTGER1 | |
| SCHEMBL2097653 | 0.71 | IDO1 (0.65) | SMN1; SMN2HTTHPGDLMNARAB9A | |
| SCHEMBL21548891 | 0.70 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTP2RX7LMNARAB9A | |
| SCHEMBL11564945 | 0.69 | ALDH1A1 (0.44) | LMNARAB9AALDH1A1 | |
| SCHEMBL2656600 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTP2RX7LMNARAB9A | |
| SCHEMBL27960158 | 0.68 | HTT (0.49) | SMN1; SMN2HTTNPSR1HPGDLMNA | |
| SCHEMBL15497186 | 0.67 | LMNA (0.67) | SMN1; SMN2HTTP2RX7LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168379-A | Pyridin-3-ols | BASF AKTIENGESELLSCHAFT (DE) | 1979-09-18 | — | — | US | disclosed |