Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558696 | 0.84 | CYP1A1 (0.49) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL11564062 | 0.82 | PDE4B (0.38) | CYP1A1CYP1B1CYP1A2KDM4EAURKA | |
| SCHEMBL11559463 | 0.80 | CYP1A2 (0.47) | CYP1A1CYP1B1CYP1A2KDM4EAURKA | |
| SCHEMBL11565251 | 0.77 | TNKS (0.55) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL11565093 | 0.74 | TNKS (0.55) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL11563071 | 0.71 | ALDH1A1 (0.39) | CYP1A1CYP1B1CYP1A2KDM4EAURKA | |
| SCHEMBL910340 | 0.68 | CYP1A1 (0.54) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL909679 | 0.67 | CYP1A1 (0.59) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL12556193 | 0.67 | TERT (0.71) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A | |
| SCHEMBL11558265 | 0.67 | CYP1A1 (0.36) | CYP1A1CYP1B1CYP1A2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148900-A | ANTIALLERGIC | CARLO ERBA S.P.A. (IT) | 1979-04-10 | — | — | US | claimed |
| US-4148900-A | ANTIALLERGIC | CARLO ERBA S.P.A. (IT) | 1979-04-10 | — | — | US | disclosed |
| US-4115567-A | TREATMENT OF ALLERGIES | CARLO ERBA S. P. A. (IT) | 1978-09-19 | — | — | US | disclosed |
| US-4083953-A | ANTIALLERGENS | CARLO ERBA, S.P.A. (IT) | 1978-04-11 | — | — | US | disclosed |
| US-4065467-A | ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS | CARLO ERBA, S. P. A. (IT) | 1977-12-27 | — | — | US | disclosed |