Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555808 | 0.86 | CYP1A2 (0.39) | RENACE | |
| SCHEMBL11557793 | 0.86 | — | — | |
| SCHEMBL11560675 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL10957286 | 0.73 | OPRM1 (0.40) | — | |
| SCHEMBL28426667 | 0.73 | OPRM1 (0.40) | — | |
| SCHEMBL10039814 | 0.71 | NPSR1 (0.41) | — | |
| SCHEMBL2972762 | 0.71 | NPSR1 (0.41) | — | |
| SCHEMBL359078 | 0.71 | NPSR1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL17393362 | 0.71 | OPRM1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL17393359 | 0.71 | OPRM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154937-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128653-A | Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4086338-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4052511-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-04 | — | — | US | disclosed |