SCHEMBL359078

SCHEMBL359078

COC(=O)[C@]1(C)CCCN1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 2/20 0.34
CYP3A4 P08684 1/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PARP1 P09874 3/20 0.30
PARP2 Q9UGN5 2/20 0.30
TNKS O95271 1/20 0.30
PARP14 Q460N5 1/20 0.30
PARP10 Q53GL7 1/20 0.30
PARP12 Q9H0J9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10039814 1.00 NPSR1 (0.41) NPSR1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL2972762 1.00 NPSR1 (0.41) NPSR1CYP4F2CYP4A11MEN1KMT2A
Hydrochloric Acid SCHEMBL15967648 0.98 NPSR1 (0.39) NPSR1CYP4F2CYP4A11MEN1KMT2A
Hydrochloric Acid SCHEMBL1357772 0.98 NPSR1 (0.39) NPSR1CYP4F2CYP4A11MEN1KMT2A
Hydrochloric Acid SCHEMBL15967647 0.98 NPSR1 (0.39) NPSR1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL16068191 0.94 NPSR1 (0.44) NPSR1CYP4F2CYP4A11MEN1KMT2A
Hydrochloric Acid SCHEMBL17392829 0.92 NPSR1 (0.42) NPSR1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL11954281 0.91
SCHEMBL11295244 0.91
SCHEMBL11294916 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215225-A1 METHOD FOR THE SYNTHESIS OF 5-METHOXY-2-(2H-1,2,3-TRIAZOL-2-YL)BENZOIC ACID, A SODIUM SALT OF SAID ACID AS A SYNTHETIC INTERMEDIATE, AND USE OF THE ACID OR THE SALT THEREOF IN THE PREPARATION OF DARIDOREXANT AND CERTAIN INTERMEDIATES IN THE SYNTHESIS THEREOF MOEHS IBERICA, S.L. (ES) 2025-10-16 WO claimed
CN-113149826-A Preparation process of pelubiprofen 台州市源众药业有限公司 2021-07-23 CN claimed
WO-2008007930-A9 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2009-04-02 WO claimed
EP-4743175-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
WO-2025215225-A1 METHOD FOR THE SYNTHESIS OF 5-METHOXY-2-(2H-1,2,3-TRIAZOL-2-YL)BENZOIC ACID, A SODIUM SALT OF SAID ACID AS A SYNTHETIC INTERMEDIATE, AND USE OF THE ACID OR THE SALT THEREOF IN THE PREPARATION OF DARIDOREXANT AND CERTAIN INTERMEDIATES IN THE SYNTHESIS THEREOF MOEHS IBERICA, S.L. (ES) 2025-10-16 WO disclosed
EP-4584247-A2 HETEROATOM SUBSTITUTED CYCLIC AND ALKYL AMINES AS ACTIVATORS OF SEROTONIN RECEPTORS ATAI Therapeutics, Inc. (US) 2025-07-16 EP disclosed
US-20250223286-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO.,LTD (CN) 2025-07-10 US disclosed
CN-113365995-B Immunomodulators, compositions and methods thereof 贝达药业股份有限公司 2025-03-04 CN disclosed
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. 2025-02-13 US disclosed
WO-2025015269-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. (US) 2025-01-16 WO disclosed
US-12187713-B2 Immunomodulators, compositions and methods thereof BETTA PHARMACEUTICALS CO., LTD (CN) 2025-01-07 US disclosed
US-20070004641-A1 Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2007-01-04 US disclosed
US-20070004641-A1 Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2007-01-04 US disclosed
US-20060258663-A1 Cyclic G-2AllylProline in treatment of Parkinson's disease NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-16 US disclosed
US-20060258663-A1 Cyclic G-2AllylProline in treatment of Parkinson's disease NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-16 US disclosed
US-20060251649-A1 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-09 US disclosed
US-20060251649-A1 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-09 US disclosed
US-6943180-B2 Substituted N-arylsulfonyl-proline derivatives as potent cell adhesion inhibitors MERCK & CO., INC. (US) 2005-09-13 US disclosed
WO-2005023815-A2 NEUROPROTECTIVE BICYCLIC COMPOUNDS AND METHODS FOR THEIR USE NEUREN PHARMACEUTICALS LIMITED (NZ) 2005-03-17 WO disclosed
US-20040102478-A1 Substituted n-arylsulfonyl-proline derivatives as potent cell adhesion inhibitors MERCK & CO., INC. 2004-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250223286-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF IL2, IL5, TSLP NPSR1 1554/4885CYP4F2 483/4885CYP4A11 740/4885
US-20040102478-A1 Substituted n-arylsulfonyl-proline derivatives as potent cell adhesion inhibitors VCAM1, CD4, ICAM1 NPSR1 587/4885CYP4F2 2040/4885CYP4A11 949/4885
US-20060251649-A1 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate GRM2, GRIN2C, GRIN2A NPSR1 1486/4885CYP4F2 2227/4885CYP4A11 3884/4885
US-12187713-B2 Immunomodulators, compositions and methods thereof IL2, TSLP, CD74 NPSR1 1942/4885CYP4F2 598/4885CYP4A11 1096/4885
US-20060258663-A1 Cyclic G-2AllylProline in treatment of Parkinson's disease PARK7, ADCYAP1R1, LRRK2 NPSR1 613/4885CYP4F2 4783/4885CYP4A11 4569/4885
US-20070004641-A1 Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate CHAT, GAP43, BCHE NPSR1 955/4885CYP4F2 4127/4885CYP4A11 3920/4885
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS IAPP, GIPR, GPR119 NPSR1 117/4885CYP4F2 4390/4885CYP4A11 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.