Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560418 | 1.00 | CYP19A1 (0.56) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL11565043 | 0.88 | ALDH1A1 (0.55) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL11565038 | 0.88 | ALDH1A1 (0.55) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL1503906 | 0.84 | ALDH1A1 (0.71) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL11559445 | 0.79 | NPC1 (0.55) | CYP19A1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL11559448 | 0.79 | NPC1 (0.55) | CYP19A1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL10979861 | 0.78 | ALDH1A1 (0.60) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL27972060 | 0.77 | ALDH1A1 (0.55) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL7921628 | 0.76 | MAPT (0.37) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL9416849 | 0.75 | ALDH1A1 (0.56) | CYP19A1ALDH1A1GAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147528-A | 6-Oxopyrimidine plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-04-03 | — | — | US | disclosed |