SCHEMBL7921628

SCHEMBL7921628

CCON=Cc1cc(NC(=O)/C(C(=O)OCC)=C(/C)N)ccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
CYP19A1 P11511 3/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
RORC P51449 1/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
GPR35 Q9HC97 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11560427 0.76 CYP19A1 (0.56) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL11560418 0.76 CYP19A1 (0.56) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL7931184 0.69 KMT2A (0.42) MAPTKMT2AALDH1A1HPGDGAA
SCHEMBL7931186 0.69 KMT2A (0.42) MAPTKMT2AALDH1A1HPGDGAA
SCHEMBL11060072 0.68 MAPT (0.60) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL14455041 0.68 MAPT (0.54) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL11565038 0.66 ALDH1A1 (0.55) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL11565043 0.66 ALDH1A1 (0.55) MAPTKMT2AALDH1A1HPGDCYP19A1
SCHEMBL7933664 0.66 DGAT1 (0.48) MAPTKMT2AALDH1A1HPGDSMN1; SMN2
SCHEMBL7933665 0.66 DGAT1 (0.48) MAPTKMT2AALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 EP disclosed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 MAPT 4647/4885KMT2A 3480/4885ALDH1A1 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.