Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304872 | 0.87 | PDE1A (0.46) | MAPK14XDHCYP1A2PDE5APDE1A | |
| SCHEMBL11559511 | 0.85 | CYP1A2 (0.45) | NOTUMMAPK14IDO1XDHCYP1A2 | |
| SCHEMBL11304795 | 0.75 | APOBEC3G (0.44) | NOTUMMAPTXDHKMT2ANPC1 | |
| SCHEMBL11318189 | 0.74 | PDE5A (0.51) | METAP2MAPTHPGDKMT2APDE5A | |
| SCHEMBL7702569 | 0.74 | XDH (0.33) | XDHPARP10PDE5APDE1APDE1B | |
| SCHEMBL11307473 | 0.74 | NOTUM (0.43) | NOTUMMAPTPDE5APDE1APDE1B | |
| SCHEMBL11304796 | 0.71 | PDE1A (0.45) | MAPK14MAPTXDHHPGDCYP1A2 | |
| SCHEMBL11312714 | 0.71 | PDE1A (0.45) | MAPK14METAP2MAPTXDHHPGD | |
| SCHEMBL11564715 | 0.71 | PDE1A (0.39) | MAPK14MAPTXDHHPGDCYP1A2 | |
| SCHEMBL11309222 | 0.70 | AKT1 (0.40) | HPGDPPARGNCOA2NCOA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | claimed |
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | disclosed |