Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307782 | 0.80 | XDH (0.31) | XDHPDE5APDE1APDE1BPDE3B | |
| SCHEMBL7702068 | 0.78 | KDM4E (0.35) | ALDH1A1PARP10 | |
| SCHEMBL11304872 | 0.77 | PDE1A (0.46) | XDHALDH1A1PDE5APDE1APDE1B | |
| SCHEMBL11080771 | 0.77 | PDE10A (0.43) | XDHPDE5APDE1APDE1BPDE3B | |
| SCHEMBL11563762 | 0.75 | KMT2A (0.40) | PDE5APDE1APDE1BPDE3BPDE1C | |
| SCHEMBL11560504 | 0.74 | NOTUM (0.43) | XDHPDE5APDE1APDE1BPDE3B | |
| SCHEMBL11304795 | 0.71 | APOBEC3G (0.44) | XDHALDH1A1POLB | |
| SCHEMBL25410369 | 0.70 | CHEK1 (0.37) | XDHALDH1A1TSHRCHEK1PARP10 | |
| SCHEMBL31687853 | 0.69 | CHEK1 (0.32) | CHEK1 | |
| SCHEMBL7701725 | 0.68 | MAPK8 (0.33) | XDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081473-A1 | SUBSTITUTED AZOLOAZIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-RE30511-E | ENZYME INHIBITOR, HERBICIDE, CYCLIZATION | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4124766-A | INTERMEDIATES FOR PHOSPHODIESTERASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4107307-A | ENZYME INHIBITORS, HERBICIDES, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |