SCHEMBL11560722

SCHEMBL11560722

O=C(NC(=O)c1cnc(Cl)cc1Cl)Nc1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGL P06737 6/20 0.56
NPC1 O15118 2/20 0.54
RAB9A P51151 1/20 0.54
HTT P42858 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 1/20 0.48
EPHX1 P07099 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CHRM1 P11229 1/20 0.48
SLC6A2 P23975 1/20 0.48
PDE4A P27815 1/20 0.48
EPHX2 P34913 1/20 0.48
ADRA1A P35348 1/20 0.48
OPRM1 P35372 1/20 0.48
PDE3A Q14432 1/20 0.48
NLRP3 Q96P20 1/20 0.48
PCTP Q9UKL6 5/20 0.47
STARD10 Q9Y365 3/20 0.47
STARD7 Q9NQZ5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13235136 0.79 RAB9A (0.56) PYGLNPC1RAB9AHTTMEN1
SCHEMBL11560094 0.79 ROCK2 (0.64) PYGLNPC1RAB9AHTTMEN1
SCHEMBL11555293 0.77 KCNQ3 (0.64) NPC1RAB9AHTTMEN1KMT2A
SCHEMBL31171311 0.77 JAK2 (0.56) RAB9AMEN1KMT2ALMNAKCNQ3
SCHEMBL31171387 0.76 KCNQ3 (0.51) PYGLRAB9AMEN1KMT2AKCNQ3
SCHEMBL31171344 0.75 ROCK2 (0.68) HTTMEN1KMT2AKDM4E
SCHEMBL23846640 0.75 KCNQ3 (0.46) NPC1RAB9AKMT2ALMNAKCNQ3
SCHEMBL11556584 0.75 NPC1 (0.54) PYGLNPC1RAB9AHTTMEN1
Chlorbenzuron SCHEMBL5177776 0.75 GCGR (0.68) PYGLNPC1RAB9AMEN1KMT2A
SCHEMBL11558369 0.74 NPC1 (0.57) PYGLNPC1RAB9AHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148902-A N-[(optionally substituted phenylamino)carbonyl] pyridine carboxamides and insecticidal use thereof THE DOW CHEMICAL COMPANY (US) 1979-04-10 US claimed