Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396850 | 0.90 | LMNA (0.62) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11561710 | 0.86 | MAOB (0.53) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11563707 | 0.86 | MAOB (0.51) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11590776 | 0.85 | MAOB (0.48) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11396830 | 0.84 | LMNA (0.61) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL7277404 | 0.84 | TSHR (0.61) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11557558 | 0.81 | MAOB (0.60) | MAOBPTGS2MAOA | |
| SCHEMBL11567569 | 0.80 | ALOX15 (0.41) | LMNATSHRHTTMAOBMAOA | |
| SCHEMBL11567039 | 0.80 | MAPT (0.54) | LMNATSHRHTTMAOBALDH1A1 | |
| SCHEMBL11589633 | 0.76 | PTPN1 (0.50) | LMNATSHRHTTMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |