Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | CCND3 | P30281 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561483 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11558880 | 0.81 | EGFR (0.39) | CCNT1CDK9CDK4CCND1CCND3 | |
| SCHEMBL11555842 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1LMNARAB9AMAPT | |
| SCHEMBL4882909 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11561909 | 0.79 | LMNA (0.44) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL24463160 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL30390474 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL23302246 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL13916682 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11556727 | 0.72 | GLP1R (0.35) | KDM4EALDH1A1LMNAHSD11B1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177057-A | PREEMERGENT OR POSTEMERGENT SELECTIVITY | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |