Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531937 | 0.84 | CA12 (0.45) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24401657 | 0.84 | CA12 (0.45) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11557056 | 0.79 | CLK1 (0.53) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30269611 | 0.79 | CLK1 (0.53) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11554953 | 0.78 | CLK1 (0.52) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9777680 | 0.77 | SMN1; SMN2 (0.52) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11964418 | 0.74 | HTT (0.47) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL9777594 | 0.71 | LMNA (0.44) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14446507 | 0.70 | LMNA (0.60) | ALDH1A1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL9777628 | 0.69 | LMNA (0.41) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4000286-A | ANALGESICS, ANTIINFLAMMATORY AND ANTIPYRETIC AGENTS | MERCK & CO., INC. (US) | 1976-12-28 | — | — | US | disclosed |