Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571844 | 0.92 | KDM4E (0.62) | ALDH1A1KDM4EHRH3 | |
| SCHEMBL27583958 | 0.90 | HRH3 (0.57) | SIGMAR1ALDH1A1HRH3CYP1A2CHRM2 | |
| SCHEMBL5604414 | 0.89 | KDM4E (0.62) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11602807 | 0.88 | KDM4E (0.60) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11606453 | 0.88 | KDM4E (0.60) | ALDH1A1KDM4E | |
| SCHEMBL7792473 | 0.84 | ALDH1A1 (0.54) | SIGMAR1ACHEALDH1A1KDM4EHTT | |
| SCHEMBL1797679 | 0.83 | HRH3 (0.67) | HRH3KCNH2 | |
| SCHEMBL1796426 | 0.83 | HRH3 (0.71) | HRH3KCNH2 | |
| SCHEMBL1795697 | 0.82 | HRH3 (0.73) | HRH3KCNH2 | |
| SCHEMBL1794620 | 0.81 | HRH3 (0.67) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169897-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4059702-A | ANTIVIRAL | RICHARDSON-MERRELL INC. (US) | 1977-11-22 | — | — | US | disclosed |