Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261528 | 0.90 | TTR (0.62) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675297 | 0.90 | KDM4E (0.68) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675525 | 0.89 | HDAC6 (0.63) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL445014 | 0.86 | HDAC6 (0.74) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675435 | 0.85 | HPSE (0.62) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675388 | 0.85 | SMN1; SMN2 (0.68) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4886394 | 0.84 | HPSE (0.63) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675296 | 0.84 | ALDH1A1 (0.67) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1675540 | 0.83 | HDAC6 (0.71) | HPSENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3401206 | 0.83 | RAB9A (0.79) | NPC1RAB9ASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024225738-A1 | BENZOXAZOLE DERIVATIVE COMPOUND HAVING DUAL AGONISTIC ACTIVITY ON FXR/PPAR ALPHA FOR TREATMENT OR PREVENTION OF FATTY LIVER DISEASE | 부산대학교 산학협력단 | 2024-10-31 | — | — | WO | claimed |
| WO-2024225738-A1 | BENZOXAZOLE DERIVATIVE COMPOUND HAVING DUAL AGONISTIC ACTIVITY ON FXR/PPAR ALPHA FOR TREATMENT OR PREVENTION OF FATTY LIVER DISEASE | 부산대학교 산학협력단 | 2024-10-31 | — | — | WO | disclosed |
| US-4169837-A | BICHROMOPHORIC BENZOXAZOLE ULTRAVIOLET STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4029670-A | Polychromophoric heterocyclic ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1977-06-14 | — | — | US | disclosed |