Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 13/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 13/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 13/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139269 | 0.95 | HCRTR2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3122087 | 0.86 | ALDH1A1 (0.39) | ALDH1A1FKBP1ATHRBATML3MBTL1 | |
| SCHEMBL25759294 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HCRTR2FKBP1ATHRBATM | |
| SCHEMBL11563078 | 0.83 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11479423 | 0.83 | HCRTR2 (0.41) | ALDH1A1HCRTR2FKBP1ATHRBATM | |
| SCHEMBL11477344 | 0.82 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14126523 | 0.81 | FKBP1A (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL23795169 | 0.80 | ALDH1A1 (0.38) | ALDH1A1THRBATML3MBTL1 | |
| SCHEMBL11478670 | 0.79 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27412105 | 0.79 | HPGD (0.46) | ALDH1A1FKBP1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149941-A | ELECTROLYTIC ALKOXYLATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4118500-A | Fungicidal alkoxy mono- and dialkoxy N-substituted cyclic amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |