Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566986 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1MAPTABCB11LMNA | |
| SCHEMBL11564081 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1MAPTABCB11LMNA | |
| SCHEMBL11565428 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1MAPTABCB11LMNA | |
| SCHEMBL11563365 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1MAPTABCB11LMNA | |
| SCHEMBL11567456 | 0.92 | TDP1 (0.51) | L3MBTL1TDP1MAPTABCB11LMNA | |
| SCHEMBL14672532 | 0.88 | TP53 (0.69) | L3MBTL1TDP1MAPTLMNATP53 | |
| SCHEMBL5215917 | 0.88 | TP53 (0.69) | L3MBTL1TDP1MAPTLMNATP53 | |
| SCHEMBL9636880 | 0.88 | TP53 (0.69) | L3MBTL1TDP1MAPTLMNATP53 | |
| SCHEMBL5219438 | 0.88 | TP53 (0.69) | L3MBTL1TDP1MAPTLMNATP53 | |
| SCHEMBL5215164 | 0.88 | TP53 (0.69) | L3MBTL1TDP1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154850-A | Certain di-(substituted phenoxy) alkanes and hypolipidaemic use thereof | BEECHAM GROUP LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |