SCHEMBL11564286

SCHEMBL11564286

CCOC(=O)CCc1ccc(OCCCCCCCCCCCCOc2ccc(Cl)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
LMNA P02545 2/20 0.53
ABCB11 O95342 1/20 0.53
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.52
LTA4H P09960 7/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
FFAR1 O14842 1/20 0.48
P2RY10 O00398 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566476 1.00 CYP4F2 (0.56) CYP4F2CYP4A11LMNAABCB11MAPT
SCHEMBL7279461 0.89 CYP4F2 (0.59) CYP4F2CYP4A11LMNALTA4HL3MBTL1
SCHEMBL28538108 0.87 CYP4F2 (0.60) CYP4F2CYP4A11LMNALTA4HL3MBTL1
SCHEMBL95661 0.87 CYP4F2 (0.72) CYP4F2CYP4A11LMNAMAPTKMT2A
SCHEMBL11566670 0.86 MAPT (0.58) LMNAABCB11MAPTMAPK1LTA4H
SCHEMBL11566931 0.86 MAPT (0.58) LMNAABCB11MAPTMAPK1LTA4H
SCHEMBL10730919 0.86 CYP4F2 (0.62) CYP4F2CYP4A11LMNAABCB11MAPT
SCHEMBL4435101 0.86 BRD4 (0.54) LMNAABCB11MAPTMAPK1KMT2A
SCHEMBL5498756 0.85 P2RY10 (0.57) CYP4F2CYP4A11LMNALTA4HL3MBTL1
SCHEMBL11566246 0.85 MAPT (0.54) LMNAABCB11MAPTMAPK1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154850-A Certain di-(substituted phenoxy) alkanes and hypolipidaemic use thereof BEECHAM GROUP LIMITED (GB) 1979-05-15 US disclosed