Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.72 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.72 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.47 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736489 | 0.95 | CYP4F2 (0.66) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 | |
| SCHEMBL10730919 | 0.92 | CYP4F2 (0.62) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 | |
| SCHEMBL68902 | 0.91 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1MAPTTDP1 | |
| SCHEMBL4467166 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 | |
| SCHEMBL17590526 | 0.88 | CYP4Z1 (0.59) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 | |
| SCHEMBL11243173 | 0.87 | MAPT (0.74) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 | |
| SCHEMBL11566476 | 0.87 | CYP4F2 (0.56) | CYP4F2CYP4A11MAPTLMNAKMT2A | |
| SCHEMBL11564286 | 0.87 | CYP4F2 (0.56) | CYP4F2CYP4A11MAPTLMNAKMT2A | |
| SCHEMBL11039828 | 0.87 | CYP4Z1 (0.58) | CYP4F2CYP4A11CYP4Z1MAPTTDP1 | |
| SCHEMBL3678807 | 0.87 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP4Z1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-116640104-A | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116640104-A | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-115572252-A | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-110330429-A | A kind of preparation method of chiral beta-hydroxy ester compound | 上海欣海国际贸易有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110003005-A | The method for preparing chiral beta-hydroxy carboxylate compound | 上海欣海国际贸易有限公司 | 2019-07-12 | — | — | CN | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |
| US-4138577-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138573-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138575-A | 11-Deoxy-16-phenoxy-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138576-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126754-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | CYP4F2 82/4885CYP4A11 818/4885CYP4Z1 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.