Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 8/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886267 | 0.86 | VCAM1 (0.50) | VCAM1PLA2G4BGAAXBP1ATM | |
| SCHEMBL237358 | 0.86 | VCAM1 (0.50) | VCAM1PLA2G4BGAAXBP1ATM | |
| SCHEMBL11347714 | 0.86 | VCAM1 (0.56) | VCAM1DGKAGAAXBP1ATM | |
| SCHEMBL39477 | 0.86 | VCAM1 (0.56) | VCAM1DGKAGAAXBP1ATM | |
| SCHEMBL7155322 | 0.86 | VCAM1 (0.56) | VCAM1DGKAGAAXBP1ATM | |
| SCHEMBL5027033 | 0.85 | VCAM1 (0.55) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL4346641 | 0.84 | CNR2 (0.48) | VCAM1DGKACNR2GAACNR1 | |
| SCHEMBL238103 | 0.84 | ESR1 (0.48) | VCAM1DGKADNM1 | |
| SCHEMBL11674242 | 0.83 | DGKA (0.47) | VCAM1DGKAPLA2G4BCNR2DNM1 | |
| SCHEMBL11598590 | 0.82 | VCAM1 (0.48) | VCAM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173574-A | 3,5-Ditertiary alkyl-4-hydroxyphenyl (alkyl) 6-acyloxy-4-thia hexanoates and hexenamides as antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
| US-4093591-A | FOR NATURAL RUBBER AND HOMO- AND COPOLYMERS OF MONO- AND DIOLEFINS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-06-06 | — | — | US | disclosed |