Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11565591 | 1.00 | ALOX15 (0.58) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Dodine SCHEMBL27713730 | 1.00 | ALOX15 (0.58) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL11559763 | 1.00 | ALOX15 (0.58) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL3312838 | 1.00 | ALOX15 (0.58) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL11559678 | 1.00 | ALOX15 (0.58) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL11557628 | 0.98 | ALOX15 (0.59) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL5457417 | 0.94 | ALOX15 (0.59) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL28682864 | 0.93 | ALOX15 (0.51) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| SCHEMBL8752673 | 0.92 | MEN1 (0.55) | ALOX15EPHX1SPHK1MEN1CYP1A2 | |
| SCHEMBL1249217 | 0.92 | MEN1 (0.55) | ALOX15EPHX1SPHK1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4045483-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4009163-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3988370-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1976-10-26 | — | — | US | disclosed |