Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 5/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565575 | 0.90 | TNKS (0.46) | TNKSTTRPIM1PIM2CALM1 | |
| SCHEMBL11558273 | 0.84 | TNKS (0.53) | TNKSQPCTTTRCYP19A1AKR1B1 | |
| SCHEMBL11565093 | 0.80 | TNKS (0.55) | TNKSQPCTTTRCYP19A1AKR1B1 | |
| SCHEMBL6497044 | 0.74 | TNKS (0.74) | TNKSQPCTTTRCYP19A1AKR1B1 | |
| SCHEMBL11561361 | 0.73 | AHR (0.56) | TNKSTTRCYP1A2CALM1PKM | |
| SCHEMBL11564062 | 0.73 | PDE4B (0.38) | PIM1PIM2CYP1A2CYP1B1KDM4E | |
| SCHEMBL11558265 | 0.71 | CYP1A1 (0.36) | TNKSPIM1PIM2CYP1A2CYP1B1 | |
| SCHEMBL11561056 | 0.71 | ALDH1A1 (0.53) | TNKSTTRCYP19A1AKR1B1MAOA | |
| SCHEMBL16377338 | 0.71 | ROCK2 (0.60) | TTRPARP1CSNK2A1 | |
| SCHEMBL11382936 | 0.70 | PIM1 (0.45) | TTRPIM1PIM2MAOACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115567-A | TREATMENT OF ALLERGIES | CARLO ERBA S. P. A. (IT) | 1978-09-19 | — | — | US | claimed |
| US-4148900-A | ANTIALLERGIC | CARLO ERBA S.P.A. (IT) | 1979-04-10 | — | — | US | disclosed |
| US-4115567-A | TREATMENT OF ALLERGIES | CARLO ERBA S. P. A. (IT) | 1978-09-19 | — | — | US | disclosed |
| US-4083953-A | ANTIALLERGENS | CARLO ERBA, S.P.A. (IT) | 1978-04-11 | — | — | US | disclosed |
| US-4065467-A | ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS | CARLO ERBA, S. P. A. (IT) | 1977-12-27 | — | — | US | disclosed |