Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905925 | 0.89 | PPIP5K2 (0.35) | PPIP5K2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL53 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methyl Alcohol SCHEMBL27921533 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| Ammonia Solution, Strong SCHEMBL28095870 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL27857212 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL28150408 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| Water SCHEMBL28182624 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| Hydrogen Peroxide SCHEMBL28819174 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| Chloromethane SCHEMBL28080032 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL28296346 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114214375-B | Process for the preparation of (R) -3- (4-halo-1H-pyrazol-1-yl) -3-cyclopentylpropionate | 江苏威凯尔医药科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116854768-A | Preparation method of Nemactetvir and intermediate thereof | 浙江九洲药业股份有限公司 | 2023-10-10 | — | — | CN | claimed |
| WO-2023125373-A1 | METHOD FOR PREPARING RUXOLITINIB AND INTERMEDIATE THEREOF | 江苏威凯尔医药科技有限公司 | 2023-07-06 | — | — | WO | claimed |
| CN-114214375-A | Preparation method of (R) -3- (4-halo-1H-pyrazol-1-yl) -3-cyclopentyl propionate | 江苏威凯尔医药科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-104370749-B | The preparation method of 2-cyclopropylethyI amine | ALCHEM PHARMTECH, INC. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104370749-A | Preparation method of 2-cyclopropyl ethylamine | SUZHOU ALCHEM PHARMTECH INC | 2015-02-25 | — | — | CN | claimed |
| CN-102311417-B | Method for preparing benzodihydropyran compound | CHENGDU HONGDA PHARMACEUTICAL CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-102311417-A | Method for preparing benzodihydropyran compound | CHENGDU HONGDA PHARMACEUTICAL CO LTD | 2012-01-11 | — | — | CN | claimed |
| CN-114214375-B | Process for the preparation of (R) -3- (4-halo-1H-pyrazol-1-yl) -3-cyclopentylpropionate | 江苏威凯尔医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-116854768-A | Preparation method of Nemactetvir and intermediate thereof | 浙江九洲药业股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116178716-B | Polyisonimide and preparation method and application thereof | 广州奥松电子股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023125373-A1 | METHOD FOR PREPARING RUXOLITINIB AND INTERMEDIATE THEREOF | 江苏威凯尔医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-116178716-A | Polyisonimide and preparation method and application thereof | 广州奥松电子股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-114214375-A | Preparation method of (R) -3- (4-halo-1H-pyrazol-1-yl) -3-cyclopentyl propionate | 江苏威凯尔医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-100503566-C | Cytosolic phospholipase A2 inhibitors | WYETH CORP (US) | 2009-06-24 | — | — | CN | disclosed |
| CN-101307013-A | Aromatic diamine with phthalonitrile pendant group, preparation method thereof and polyimides or polyamide prepared therefrom | UNIV SICHUAN (CN) | 2008-11-19 | — | — | CN | disclosed |
| CN-1617855-A | Cytosolic phospholipase A2Inhibitors | WYETH CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| US-4162319-A | ANTHELMINTICS, PSYCHOTROPIC, CNS, HYPOGLYCOMIC AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-07-24 | — | — | US | disclosed |
| US-4120961-A | ANTIHELMINTICS, CNS ACITVITY | E. MERCK (DE) | 1978-10-17 | — | — | US | disclosed |
| US-4051243-A | RING SUBSTITUTED PYRAZINO-ISOQUINOLINE DERIVATIVES AND THEIR PREPARATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |