Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | IL18 | Q14116 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077987 | 0.92 | GSK3B (0.47) | MAPTKDM4EMEN1LMNAPOLB | |
| SCHEMBL11565671 | 0.86 | PARP15 (0.47) | MAPTKDM4EMEN1LMNAPOLB | |
| SCHEMBL1565875 | 0.81 | MAPK1 (0.51) | MAPK1RAB9AKMT2APARP10ALDH1A1 | |
| SCHEMBL11562437 | 0.80 | FNTA (0.45) | FNTAFNTBALDH1A1MMP2MMP1 | |
| SCHEMBL11562352 | 0.78 | MAPT (0.45) | MAPTMEN1LMNAMAPK1RAB9A | |
| SCHEMBL378101 | 0.77 | KMT2A (0.49) | MEN1RAB9AKMT2AHTTALDH1A1 | |
| SCHEMBL9259272 | 0.77 | GSK3B (0.45) | MAPTKDM4EMEN1RAB9AKMT2A | |
| SCHEMBL11564622 | 0.77 | LMNA (0.40) | MEN1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL31232337 | 0.77 | SCN9A (0.37) | LMNAMAPK1ALDH1A1SCN9A | |
| SCHEMBL11568416 | 0.76 | LMNA (0.45) | MAPTKDM4EMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |