Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550706 | 0.92 | ENPP2 (0.42) | LMNAAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL1565875 | 0.81 | MAPK1 (0.51) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11562437 | 0.80 | FNTA (0.45) | ALDH1A1MMP9MMP2MMP14MMP1 | |
| SCHEMBL184992 | 0.78 | CA12 (0.40) | SMN1; SMN2ALDH1A1MMP13MMP1KMT2A | |
| SCHEMBL11566175 | 0.78 | KMT2A (0.52) | LMNASMN1; SMN2HTTPOLBPTGS2 | |
| SCHEMBL11562352 | 0.78 | MAPT (0.45) | LMNASMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL378101 | 0.77 | KMT2A (0.49) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11567634 | 0.77 | EPHX2 (0.44) | MMP9MMP2PTGS2MMP13MMP1 | |
| SCHEMBL11568045 | 0.77 | PTGS2 (0.44) | MMP9MMP2PTGS2MMP13MMP1 | |
| SCHEMBL11564487 | 0.77 | MAPT (0.51) | LMNAHTTALDH1A1POLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |