Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | NSD2 | O96028 | 8/20 | 0.54 |
| ▸ | NSD3 | Q9BZ95 | 5/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016926 | 0.88 | ADORA2A (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL9373694 | 0.83 | PDE4A (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21788552 | 0.81 | ADORA2A (0.76) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11017113 | 0.78 | HDAC6 (0.57) | PDE5APDE4APDE1APDE1BPDE4B | |
| SCHEMBL11813045 | 0.77 | ADORA2A (0.70) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6659204 | 0.77 | ADORA2A (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL31379008 | 0.76 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL31025603 | 0.76 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL8375355 | 0.76 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL126655 | 0.76 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171440-A | Process for purification of 9-(2,6-dihalobenzyl)adenines | MERCK & CO., INC. (US) | 1979-10-16 | — | — | US | disclosed |