Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 14/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395769 | 0.85 | SLC29A1 (0.54) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL141541 | 0.85 | SLC29A1 (0.54) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL9565592 | 0.80 | SLC29A1 (0.49) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL15065643 | 0.79 | SLC29A1 (0.48) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL7446838 | 0.78 | SLC29A1 (0.47) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL1956785 | 0.75 | SLC29A1 (0.41) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL6555164 | 0.75 | SMN1; SMN2 (0.39) | KDM4EUSP2ALDH1A1LMNAGAA | |
| SCHEMBL4077875 | 0.74 | SLC29A1 (0.43) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL9351966 | 0.73 | SLC29A1 (0.56) | SLC29A1KDM4EMEN1PDE2ARGS12 | |
| SCHEMBL2458640 | 0.72 | SLC29A1 (0.41) | SLC29A1KDM4EMEN1PDE2ARGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147789-A | ANTIPARKINSON AGENTS | SANDOZ LTD. (CH) | 1979-04-03 | — | — | US | disclosed |