Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564661 | 0.75 | SLC29A1 (0.42) | SMN1; SMN2LMNATSHRKMT2ACRHR1 | |
| SCHEMBL141541 | 0.72 | SLC29A1 (0.54) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL3395769 | 0.72 | SLC29A1 (0.54) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL9565592 | 0.68 | SLC29A1 (0.49) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL15065643 | 0.67 | SLC29A1 (0.48) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL1956785 | 0.66 | SLC29A1 (0.41) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL7446838 | 0.66 | SLC29A1 (0.47) | SMN1; SMN2LMNATSHRKMT2AKDM4E | |
| SCHEMBL4077875 | 0.65 | SLC29A1 (0.43) | SMN1; SMN2LMNATSHRCYP1A2KMT2A | |
| SCHEMBL275457 | 0.64 | LMNA (0.35) | LMNACYP1A2HSD17B10 | |
| SCHEMBL24851760 | 0.63 | CHRM3 (0.41) | SMN1; SMN2LMNATSHRCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108898-B1 | ORAL GALENICAL FORMS OF MOPIDAMOL | Dr. Karl Thomae GmbH (DE) | 1986-08-20 | — | — | EP | claimed |
| US-4285945-A | SYNERGISTIC MIXTURE OF 2,6-BIS/DIETHANOLAMINO/-4-PIPERIDINO-PYRIMIDO/5,4-D/PYRIMIDINE AND SULFINPYRAZONE | SLICHTER SHERRILL J | 1981-08-25 | — | — | US | claimed |
| EP-1389112-A2 | USE OF RADICAL SCAVENGING COMPOUNDS FOR TREATMENT AND PREVENTION OF NO-DEPENDENT MICROCIRCULATION DISORDERS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002085368-A2 | USE OF RADICAL SCAVENGING COMPOUNDS FOR TREATMENT AND PREVENTION OF NO-DEPENDENT MICROCIRCULATION DISORDERS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-10-31 | — | — | WO | disclosed |
| EP-1225900-A1 | USE OF DIPYRIDAMOLE OR MOPIDAMOL IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT AND PREVENTION OF FIBRIN-DEPENDENT MICROCIRCULATION DISORDERS | Boehringer Ingelheim Pharma KG (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001030353-A1 | USE OF DIPYRIDAMOLE OR MOPIDAMOL IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT AND PREVENTION OF FIBRIN-DEPENDENT MICROCIRCULATION DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-05-03 | — | — | WO | disclosed |
| US-4285945-A | SYNERGISTIC MIXTURE OF 2,6-BIS/DIETHANOLAMINO/-4-PIPERIDINO-PYRIMIDO/5,4-D/PYRIMIDINE AND SULFINPYRAZONE | SLICHTER SHERRILL J | 1981-08-25 | — | — | US | disclosed |