Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518534 | 0.93 | CYP2C9 (0.51) | HSD17B10CYP2C9CYP2C19SLC6A3TSHR | |
| SCHEMBL11565596 | 0.86 | CYP2C9 (0.45) | HSD17B10CYP2C9CYP2C19SLC6A3TSHR | |
| SCHEMBL28695278 | 0.85 | LMNA (0.53) | HSD17B10CYP2C9CYP2C19L3MBTL1TRPA1 | |
| SCHEMBL28695277 | 0.85 | LMNA (0.53) | HSD17B10CYP2C9CYP2C19L3MBTL1TRPA1 | |
| SCHEMBL11565126 | 0.81 | UTS2R (0.45) | HSD17B10CYP2C9CYP2C19L3MBTL1LMNA | |
| SCHEMBL11562550 | 0.80 | LMNA (0.47) | HSD17B10CYP2C9CYP2C19L3MBTL1LMNA | |
| SCHEMBL28600328 | 0.78 | CYP2C9 (0.61) | HSD17B10CYP2C9CYP2C19SLC6A3TSHR | |
| SCHEMBL3521016 | 0.76 | CYP2C9 (0.63) | HSD17B10CYP2C9CYP2C19TSHRL3MBTL1 | |
| SCHEMBL11761904 | 0.75 | TRPA1 (0.51) | HSD17B10CYP2C9CYP2C19TRPA1HPGD | |
| SCHEMBL933765 | 0.75 | TRPA1 (0.51) | HSD17B10CYP2C9CYP2C19TRPA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |