Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28174260 | 0.86 | PRSS1 (0.43) | THRATHRBPRSS1HRH3F2 | |
| SCHEMBL2064722 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 | |
| SCHEMBL11238623 | 0.83 | ABL1 (0.46) | ABL1SMN1; SMN2KCNH3THRATHRB | |
| SCHEMBL1240317 | 0.82 | CA12 (0.47) | ABL1ALDH1A1KCNH3THRATHRB | |
| SCHEMBL1241959 | 0.81 | ABL1 (0.56) | ABL1ALDH1A1TSHRKCNH3PRSS1 | |
| SCHEMBL9512936 | 0.81 | ABL1 (0.47) | ABL1ALDH1A1KCNH3THRATHRB | |
| SCHEMBL10436415 | 0.80 | ABL1 (0.49) | ABL1ALDH1A1SMN1; SMN2ALOX15ALOX12 | |
| SCHEMBL31081617 | 0.80 | ABL1 (0.49) | ABL1ALDH1A1SMN1; SMN2KCNH3PRSS1 | |
| SCHEMBL187892 | 0.79 | ABL1 (0.59) | ABL1ALDH1A1TSHRKCNH3PRSS1 | |
| SCHEMBL11476522 | 0.79 | ABL1 (0.59) | ABL1ALDH1A1TSHRKCNH3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | claimed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |