Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796906 | 0.89 | OPRM1 (0.54) | OPRM1OPRK1OPRD1GAAPOLB | |
| SCHEMBL11796756 | 0.88 | OPRM1 (0.50) | OPRM1OPRK1OPRD1GAAPOLB | |
| SCHEMBL11565335 | 0.86 | KCNA3 (0.52) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL11564520 | 0.86 | KCNA3 (0.57) | OPRM1OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL11566234 | 0.84 | OPRM1 (0.45) | KDM4EOPRM1OPRK1OPRD1MEN1 | |
| SCHEMBL9737959 | 0.84 | CA12 (0.62) | OPRM1OPRK1OPRD1CA12CA1 | |
| SCHEMBL11563023 | 0.83 | KCNA3 (0.47) | OPRM1OPRK1OPRD1ALDH1A1MAPT | |
| SCHEMBL11567683 | 0.82 | KCNA3 (0.46) | KDM4EOPRM1OPRK1OPRD1MEN1 | |
| SCHEMBL11562170 | 0.82 | MEN1 (0.51) | KDM4EOPRM1OPRK1OPRD1MEN1 | |
| SCHEMBL11564236 | 0.81 | KCNA3 (0.44) | OPRM1OPRK1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |