Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565335 | 0.91 | KCNA3 (0.52) | KCNA3OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL11563023 | 0.88 | KCNA3 (0.47) | KCNA3OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL11564236 | 0.87 | KCNA3 (0.44) | KCNA3OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL11564520 | 0.85 | KCNA3 (0.57) | KCNA3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11566234 | 0.83 | OPRM1 (0.45) | KCNA3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11565124 | 0.82 | KDM4E (0.51) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL11568177 | 0.82 | CA12 (0.58) | KCNA3OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11562170 | 0.81 | MEN1 (0.51) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL11793631 | 0.80 | OPRM1 (0.44) | OPRM1OPRD1OPRK1ALDH1A1MAPK1 | |
| SCHEMBL11568693 | 0.79 | ALDH1A1 (0.41) | KCNA3OPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |