Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565489 | 0.83 | HTR1A (0.67) | HTR1ADRD2DRD4 | |
| SCHEMBL11562274 | 0.83 | HTR1A (0.73) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11565139 | 0.82 | HTR1A (0.65) | HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11567806 | 0.82 | HTR1A (0.71) | HTR1ADRD2 | |
| SCHEMBL11566082 | 0.79 | HTR1A (0.67) | HTR1ADRD2 | |
| Mezilamine SCHEMBL2109086 | 0.79 | HTR1A (1.00) | HTR1ADRD2DRD4 | |
| SCHEMBL11567684 | 0.76 | HTR1A (0.75) | HTR1ADRD2 | |
| SCHEMBL11561867 | 0.76 | HTR1A (0.70) | HTR1ADRD2DRD4 | |
| Iprozilamine SCHEMBL2108511 | 0.75 | HTR1A (0.73) | HTR1ADRD2 | |
| SCHEMBL8565639 | 0.74 | HTR1A (1.00) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166852-A | ANALGESICS, ANTISEROTONINE AGENTS, PSYCHOTROPES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1979-09-04 | — | — | US | claimed |
| US-4166852-A | ANALGESICS, ANTISEROTONINE AGENTS, PSYCHOTROPES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1979-09-04 | — | — | US | disclosed |