Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | DRD4 | P21917 | 3/20 | 1.00 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564570 | 0.90 | HTR1A (0.82) | HTR1ADRD2DRD4 | |
| SCHEMBL8563375 | 0.89 | HTR1A (0.79) | HTR1ADRD2DRD4 | |
| SCHEMBL8567179 | 0.81 | HTR1A (0.67) | HTR1ADRD2DRD4HRH4 | |
| Mezilamine SCHEMBL2109086 | 0.80 | HTR1A (1.00) | HTR1ADRD2DRD4 | |
| SCHEMBL8564591 | 0.80 | HTR1A (0.64) | HTR1ADRD2DRD4 | |
| SCHEMBL11561867 | 0.78 | HTR1A (0.70) | HTR1ADRD2DRD4 | |
| SCHEMBL8569210 | 0.77 | HTR1A (0.62) | HTR1ADRD2DRD4HRH4 | |
| SCHEMBL11565489 | 0.76 | HTR1A (0.67) | HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11565139 | 0.75 | HTR1A (0.65) | HTR1ADRD2DRD4 | |
| SCHEMBL11565197 | 0.74 | HTR1A (0.64) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |