Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153612 | 0.77 | CYP19A1 (0.48) | SMN1; SMN2MAPTHPGDCYP1A2CYP19A1 | |
| SCHEMBL11774401 | 0.76 | PNMT (0.42) | SMN1; SMN2POLBMAPTLMNAMPO | |
| SCHEMBL20267786 | 0.75 | ALDH1A1 (0.59) | SMN1; SMN2MAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL26988712 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBMAPTHPGDMEN1 | |
| SCHEMBL7090232 | 0.73 | POLB (0.47) | POLBMAPTCYP3A4MPO | |
| SCHEMBL109902 | 0.72 | MAOB (0.41) | SMN1; SMN2POLBMAPTHPGDCYP3A4 | |
| SCHEMBL29920826 | 0.72 | MAOB (0.41) | SMN1; SMN2POLBMAPTHPGDCYP3A4 | |
| SCHEMBL1758970 | 0.71 | CSNK2A1 (0.49) | POLBMAPTMEN1KMT2AALOX15 | |
| Bromide SCHEMBL7394464 | 0.70 | MAOB (0.40) | SMN1; SMN2POLBMAPTHPGDCYP3A4 | |
| SCHEMBL22231728 | 0.70 | TSHR (0.37) | CYP3A4CYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001655-A2 | Compositions comprising as active ingredients cyanobenzyl(idene)-aniline derivatives, the use of the compositions as plant growth regulants and a method for the preparation of the active ingredients | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-05-02 | — | — | EP | claimed |