Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565095 | 0.86 | CA12 (0.59) | OPRM1OPRD1OPRK1KCNA3CA12 | |
| SCHEMBL11565284 | 0.85 | KCNA3 (0.51) | OPRM1OPRD1OPRK1KCNA3CA12 | |
| SCHEMBL11563591 | 0.84 | CA12 (0.46) | OPRM1OPRD1OPRK1CA12CA1 | |
| SCHEMBL11566590 | 0.84 | CA12 (0.47) | OPRM1OPRD1OPRK1CA12CA1 | |
| SCHEMBL2985764 | 0.83 | CYP2D6 (0.60) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11455428 | 0.82 | CYP2D6 (0.58) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5333674 | 0.82 | OPRM1 (0.49) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL11568939 | 0.81 | OPRM1 (0.54) | OPRM1OPRD1OPRK1KCNA3CA12 | |
| SCHEMBL11567187 | 0.81 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KCNA3CA12 | |
| SCHEMBL11565716 | 0.81 | KCNA3 (0.54) | OPRM1OPRD1OPRK1KCNA3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |