Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11564720 | 0.99 | KCNA3 (0.53) | KCNA3CA12CA1CA2CA4 | |
| SCHEMBL11565095 | 0.94 | CA12 (0.59) | KCNA3CA12CA1CA2CA4 | |
| SCHEMBL11567187 | 0.92 | OPRM1 (0.56) | KCNA3CA12CA1CA2CA4 | |
| SCHEMBL11565171 | 0.91 | CA12 (0.55) | KCNA3CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL11562848 | 0.91 | OPRM1 (0.55) | KCNA3CA12CA1CA2CA4 | |
| SCHEMBL11565880 | 0.89 | OPRM1 (0.57) | LMNAMEN1KMT2ATDP1OPRM1 | |
| Hydrochloric Acid SCHEMBL11563849 | 0.88 | OPRM1 (0.56) | LMNAMEN1KMT2ATDP1OPRM1 | |
| SCHEMBL11566758 | 0.88 | CA12 (0.55) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11566162 | 0.86 | CA12 (0.54) | CA12CA1CA2CA4CA5A | |
| Water SCHEMBL11562720 | 0.85 | CA12 (0.53) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |