SCHEMBL1156530

SCHEMBL1156530

O=C(O)Oc1cccc(C2CCCCC2)c1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.52
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPN5 P54829 3/20 0.39
PTPN2 P17706 1/20 0.39
FAAH O00519 2/20 0.39
MGLL Q99685 1/20 0.39
SLC6A9 P48067 1/20 0.39
PTGDR Q13258 2/20 0.39
KMO O15229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712179 0.91 PTGDR2 (0.46) PTGDR2FAAHSLC6A9PTGDR
SCHEMBL789205 0.85 PTGDR2 (0.65) PTGDR2MEN1KMT2APTGDR
SCHEMBL28006501 0.83 PTGDR2 (0.62) PTGDR2MEN1KMT2APTGDR
SCHEMBL247376 0.81 PTGDR2 (0.52) PTGDR2MEN1KMT2APTGDRKMO
SCHEMBL1156531 0.79 PTGDR2 (0.55) PTGDR2MEN1KMT2APTGDR
SCHEMBL14775519 0.79 PTGDR2 (0.51) PTGDR2MEN1KMT2APTGDRKMO
SCHEMBL27865683 0.79 POLB (0.46) PTGDR2PTPN5PTPN2KMO
SCHEMBL8774870 0.79 PTGDR2 (0.47) PTGDR2MEN1KMT2APTPN5PTPN2
SCHEMBL7213527 0.75 PARP1 (0.45) PTGDR2MEN1KMT2APTPN5PTPN2
SCHEMBL30215707 0.75 MEN1 (0.45) PTGDR2MEN1KMT2APTPN5PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
CN-105829396-B Preparation of siloxane-containing block copolycarbonates by reactive extrusion 科思创德国股份有限公司 2019-12-20 CN disclosed
CN-106536630-B Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties 科思创德国股份有限公司 2019-07-19 CN disclosed
CN-102666703-B Polycarbonate sheet with improved flame retardancy BAYER MATERIALSCIENCE A G 2014-12-24 CN disclosed
CN-102725341-B Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2014-09-17 CN disclosed
CN-101842429-B Flame retardant polycarbonate comprising a polyol BAYER MATERIALSCIENCE AG 2013-03-27 CN disclosed
CN-102725341-A Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2012-10-10 CN disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
CN-1454914-A Makrolan having specific branching end group, polyester carbonate ester and polyester BAYER AG (DE) 2003-11-12 CN disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
CN-1394895-A Preparation and use of polyester carbonic acid ester BAYER AG (DE) 2003-02-05 CN disclosed
CN-1390872-A polycarbonates, polyester carbonates and polyesters having branched end groups BAYER AG (DE) 2003-01-15 CN disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed