SCHEMBL247376

SCHEMBL247376

O=C(O)Oc1cccc(C2CCCCC2)c1C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 15/20 0.52
PTGDR Q13258 6/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KMO O15229 1/20 0.40
PTGER2 P43116 1/20 0.39
ABCB1 P08183 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247375 0.89 PTGDR2 (0.50) PTGDR2PTGDRMEN1KMT2AKMO
SCHEMBL789205 0.85 PTGDR2 (0.65) PTGDR2PTGDRMEN1KMT2APTGER2
SCHEMBL28006501 0.83 PTGDR2 (0.62) PTGDR2PTGDRMEN1KMT2APTGER2
SCHEMBL14775410 0.83 CXCR5 (0.43) PTGDR2MEN1KMT2AKMOABCB1
SCHEMBL14775519 0.83 PTGDR2 (0.51) PTGDR2PTGDRMEN1KMT2AKMO
SCHEMBL5839212 0.82 PTGDR2 (0.45) PTGDR2PTGDRMEN1KMT2AABCB1
SCHEMBL5838999 0.82 PTGDR2 (0.45) PTGDR2PTGDRMEN1KMT2AKMO
SCHEMBL1156530 0.81 PTGDR2 (0.52) PTGDR2PTGDRMEN1KMT2AKMO
SCHEMBL14775345 0.81 PTGDR2 (0.43) PTGDR2MEN1KMT2AKMOABCB1
SCHEMBL3679820 0.80 PTGDR2 (0.46) PTGDR2PTGDRMEN1KMT2AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
EP-3452530-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
US-9676716-B2 Polycarbonate having improved thermal and mechanical properties and reduced coefficients of thermal expansion COVESTRO DEUTSCHLAND AG (DE) 2017-06-13 US disclosed
US-20150232644-A1 PRODUCTS WITH IMPROVED NON-FLAMMABILITY COVESTRO DEUTSCHLAND AG (DE) 2015-08-20 US disclosed
US-8969477-B2 Polycarbonate compositions having improved mechanical properties BAYER MATERIALSCIENCE AG (DE) 2015-03-03 US disclosed
US-8507635-B2 Modified polycarbonates having improved surface properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-13 US disclosed
US-8470934-B2 Polycarbonate compositions having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2013-06-25 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-6630563-B2 Oligocarbonates produced by catalytic transesterification of diaryl carbonate with dihydroxyaryl compound; enables continuous formation of free films BAYER AKTIENGESELLSCHAFT (DE) 2003-10-07 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20030096941-A1 Polycarbonates, polyester carbonates and polyesters having branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2003-05-22 US disclosed
US-20030055201-A1 Process for optimising the production of polycarbonate by melt transesterification BAYER AKTIENGESELLSCHAFT (DE) 2003-03-20 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20020188091-A1 Process for continuous production of polycarbonates and a reactor therefor COVESTRO DEUTSCHLAND AG (DE) 2002-12-12 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed