SCHEMBL1156531

SCHEMBL1156531

O=C(O)Oc1ccccc1-c1ccccc1C1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 9/20 0.55
PTGS2 P35354 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NAAA Q02083 1/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
PTGDR Q13258 4/20 0.38
PTGER2 P43116 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156529 0.89 PTGDR2 (0.52) PTGDR2PTGS2MEN1KMT2ANAAA
SCHEMBL789205 0.87 PTGDR2 (0.65) PTGDR2MEN1KMT2APTGDRPTGER2
SCHEMBL28006501 0.85 PTGDR2 (0.62) PTGDR2MEN1KMT2APTGDRPTGER2
SCHEMBL233919 0.81 S1PR1 (0.46) PTGDR2MEN1KMT2AALDH1A1RAB9A
SCHEMBL247376 0.80 PTGDR2 (0.52) PTGDR2MEN1KMT2APTGDRPTGER2
SCHEMBL1156530 0.79 PTGDR2 (0.52) PTGDR2MEN1KMT2APTGDR
SCHEMBL14775519 0.79 PTGDR2 (0.51) PTGDR2MEN1KMT2APTGDRPTGER2
SCHEMBL4476575 0.78 PTGS2 (0.56) PTGDR2PTGS2BCHEACHE
SCHEMBL7017642 0.78 FABP3 (0.44) PTGDR2PTGS2KMT2AALDH1A1
SCHEMBL8774864 0.76 PTGDR2 (0.48) PTGDR2PTGS2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
EP-3452530-B1 COPOLYCARBONATE AS SUPPORT MATERIAL FOR 3D PRINTING COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-09-30 EP disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
CN-105829396-B Preparation of siloxane-containing block copolycarbonates by reactive extrusion 科思创德国股份有限公司 2019-12-20 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-8044122-B2 Polycarbonate composition containing UV absorber BAYER MATERIALSCIENCE AG (DE) 2011-10-25 US disclosed
US-7879967-B2 End groups containing alkylsiloxane substituted phenol compounds ; extrusion; molding materials BAYER MATERIALSCIENCE AG (DE) 2011-02-01 US disclosed
US-20090258978-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2009-10-15 US disclosed
US-6767986-B2 A LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS PREPARED AND A SECOND STAGE WHERE THE LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS CONDENSED WITH DIARYL CARBONATE IN A MELT TRANSESTERIFICATION PROCESS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US disclosed
US-20040143088-A1 Method for producing polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2004-07-22 US disclosed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed