Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784265 | 0.86 | CASP3 (0.77) | CHEK2KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL979496 | 0.86 | CASP3 (0.77) | CHEK2KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL693160 | 0.85 | F2 (0.58) | CHEK2FFAR1CASP3SENP8SENP7 | |
| SCHEMBL164956 | 0.85 | CASP3 (0.57) | CHEK2FFAR1KDM4EALDH1A1LMNA | |
| SCHEMBL11563588 | 0.85 | CASP3 (0.57) | CHEK2FFAR1KDM4EMEN1NPC1 | |
| SCHEMBL6710661 | 0.83 | HDAC6 (0.55) | CHEK2FFAR1KDM4EMEN1NPC1 | |
| SCHEMBL166322 | 0.82 | CASP3 (0.51) | CHEK2FFAR1KDM4EMEN1NPC1 | |
| SCHEMBL4334503 | 0.82 | CASP3 (0.57) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL693721 | 0.81 | CYP19A1 (0.61) | CHEK2FFAR1CYP19A1CASP3SENP8 | |
| SCHEMBL164967 | 0.81 | HPN (0.54) | CHEK2SMN1; SMN2CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169837-A | BICHROMOPHORIC BENZOXAZOLE ULTRAVIOLET STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4029670-A | Polychromophoric heterocyclic ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1977-06-14 | — | — | US | disclosed |