Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | F9 | P00740 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563277 | 0.92 | PPARG (0.43) | PPARGSLC22A12F9F10RAF1 | |
| SCHEMBL11564365 | 0.91 | PPARG (0.45) | PPARGSLC22A12F9F10PPARA | |
| SCHEMBL11563520 | 0.90 | PPARG (0.69) | PPARGSLC22A12F9F10PPARA | |
| SCHEMBL11566210 | 0.89 | PPARG (0.54) | PPARGSLC22A12F9F10RAF1 | |
| SCHEMBL11567624 | 0.88 | POLB (0.44) | PPARGSLC22A12F9F10UTS2R | |
| SCHEMBL11568422 | 0.88 | POLB (0.44) | PPARGSLC22A12F9F10UTS2R | |
| SCHEMBL11562673 | 0.88 | PPARG (0.66) | PPARGSLC22A12F9F10PPARA | |
| SCHEMBL11566988 | 0.87 | F9 (0.51) | PPARGSLC22A12F9F10PPARA | |
| SCHEMBL11584758 | 0.85 | PPARG (0.53) | PPARGSLC22A12PPARA | |
| SCHEMBL14541455 | 0.84 | PPARG (0.75) | PPARGSLC22A12F9F10PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |