Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567624 | 1.00 | POLB (0.44) | POLBPPARGSLC22A12NPC1RAB9A | |
| SCHEMBL11565422 | 0.91 | F9 (0.46) | PPARGSLC22A12F9F10MAPT | |
| SCHEMBL11564365 | 0.90 | PPARG (0.45) | POLBPPARGSLC22A12F9F10 | |
| SCHEMBL11568279 | 0.89 | POLB (0.42) | POLBPPARGSLC22A12NPC1RAB9A | |
| SCHEMBL11564430 | 0.89 | PPARG (0.51) | PPARGSLC22A12F9F10UTS2R | |
| SCHEMBL11565453 | 0.88 | PPARG (0.54) | PPARGSLC22A12F9F10UTS2R | |
| SCHEMBL11566782 | 0.88 | PPARA (0.45) | POLBPPARGSLC22A12UTS2RGCGR | |
| SCHEMBL11562974 | 0.87 | MAPT (0.56) | POLBNPC1RAB9AMAPTGCGR | |
| SCHEMBL11562897 | 0.86 | CYP2C19 (0.43) | PPARGSLC22A12SMN1; SMN2F9F10 | |
| SCHEMBL11561168 | 0.85 | PPARG (0.51) | PPARGSLC22A12F9F10UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |