Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565453 | 0.89 | PPARG (0.54) | PPARGSLC22A12PPARAALDH1A1LMNA | |
| SCHEMBL11566782 | 0.89 | PPARA (0.45) | PPARGSLC22A12PPARAABCB11CYP1A2 | |
| SCHEMBL13374099 | 0.85 | PPARG (0.72) | PPARGSLC22A12PPARAKDM4EALDH1A1 | |
| SCHEMBL11564169 | 0.84 | PPARA (0.46) | PPARGSLC22A12PPARAABCB11CYP1A2 | |
| SCHEMBL11563277 | 0.80 | PPARG (0.43) | PPARGSLC22A12ALDH1A1LMNAHTT | |
| SCHEMBL11566518 | 0.80 | KMT2A (0.45) | PPARGSLC22A12PPARAABCB11CYP1A2 | |
| SCHEMBL11564365 | 0.79 | PPARG (0.45) | PPARGSLC22A12PPARAF9F10 | |
| SCHEMBL11567643 | 0.79 | PPARG (0.46) | PPARGSLC22A12PPARAABCB11CYP1A2 | |
| SCHEMBL11639892 | 0.79 | CYP1A2 (0.42) | PPARGSLC22A12PPARAABCB11CYP1A2 | |
| SCHEMBL11598122 | 0.79 | PPARG (0.65) | PPARGSLC22A12PPARAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | claimed |