Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565456 | 1.00 | CES2 (0.52) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28391271 | 0.84 | CES2 (0.54) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11339856 | 0.84 | CES2 (0.54) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11558620 | 0.84 | CES2 (0.54) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11341276 | 0.83 | ALDH1A1 (0.66) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11341279 | 0.83 | ALDH1A1 (0.66) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11341264 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11341267 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11341677 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1LMNANPSR1 | |
| SCHEMBL11330511 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173650-A | ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-11-06 | — | — | US | claimed |