SCHEMBL11565663

SCHEMBL11565663

CC1(C(=O)Nc2ccc(OCc3ccccc3F)c(C(F)(F)F)c2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRAF P15056 1/20 0.47
KDR P35968 1/20 0.47
S1PR1 P21453 2/20 0.45
KMT2A Q03164 5/20 0.43
MAPT P10636 5/20 0.43
MEN1 O00255 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
KDM4E B2RXH2 3/20 0.43
HTT P42858 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
PAX8 Q06710 1/20 0.43
SGMS2 Q8NHU3 2/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
GAA P10253 3/20 0.40
PKM P14618 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11561946 0.86 RXRA (0.48) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11568138 0.81 MRGPRX4 (0.49) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11565226 0.80 BRAF (0.47) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11565893 0.79 BRAF (0.46) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11566813 0.79 BRAF (0.46) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11569043 0.76 KCNJ5 (0.45) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11564073 0.76 RXRA (0.48) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11050028 0.76 BRAF (0.46) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11563745 0.74 BRAF (0.44) BRAFKDRS1PR1KMT2AMAPT
SCHEMBL11566143 0.73 DHODH (0.43) BRAFKDRS1PR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166735-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1979-09-04 US disclosed