Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 5/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | ARAF | P10398 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435806 | 0.84 | PDE4B (0.41) | HPGDLMNASMN1; SMN2PDE4APDE4B | |
| SCHEMBL11565226 | 0.83 | BRAF (0.47) | BRAFKDRHPGDS1PR1KDM4E | |
| SCHEMBL11564382 | 0.83 | P2RX3 (0.49) | P2RX4RORCPDE4APDE4BPDE4C | |
| SCHEMBL11566813 | 0.82 | BRAF (0.46) | BRAFRAF1KDRHPGDS1PR1 | |
| SCHEMBL11561946 | 0.81 | RXRA (0.48) | BRAFKDRHPGDS1PR1KDM4E | |
| SCHEMBL11568138 | 0.81 | MRGPRX4 (0.49) | BRAFKDRHPGDS1PR1HTR2A | |
| SCHEMBL11050028 | 0.79 | BRAF (0.46) | BRAFKDRHPGDS1PR1KDM4E | |
| SCHEMBL11564073 | 0.79 | RXRA (0.48) | BRAFKDRTRPV1HPGDS1PR1 | |
| SCHEMBL11565663 | 0.79 | BRAF (0.47) | BRAFKDRHPGDS1PR1KDM4E | |
| SCHEMBL11563745 | 0.78 | BRAF (0.44) | BRAFKDRTRPV1HPGDS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |